New Study Suggests Viagra May Lower Risk of Alzheimer’s Disease in Men

 / 

In a promising development, a recent five-year study conducted on approximately 260,000 older adult men has unveiled a potential link between the use of erectile dysfunction medications, such as Viagra, and a reduced risk of Alzheimer’s disease.

The study, led by researchers from University College London and published in the journal Neurology, found that men taking medications like Viagra were 18% less likely to develop the neurodegenerative disease, which is characterized by memory loss, impaired thinking, and behavioral changes.

The mechanism behind this potential association lies in the way erectile dysfunction drugs function. Originally developed to treat high blood pressure, these medications work by dilating blood vessels to improve blood flow.

Viagra Directly Lowers The Risk of Alzheimer’s

The researchers hypothesize that this improved blood flow may have a protective effect on brain health, reducing the risk of Alzheimer’s disease.

Men who received between 21 to 50 prescriptions of sildenafil, the active ingredient in Viagra, throughout the study period showed a remarkable 44% lower risk of developing dementia.

However, the researchers caution that further research is needed to determine whether Viagra directly lowers the risk of Alzheimer’s or if men who choose to take Viagra already have a lower risk due to other factors.

Lead study author Dr. Ruth Brauer emphasized the need for future clinical trials to explore the effects of erectile dysfunction drugs on Alzheimer’s disease risk in both men and women.

With around 6.7 million Americans aged 65 and older affected by Alzheimer’s, any potential interventions that could reduce the risk of this devastating disease are of significant interest.

While age, alcohol consumption, and smoking are known factors that can influence the rate of Alzheimer’s disease, previous studies have also hinted at a potential link between the use of Viagra and a reduced risk of developing the disease.

A study conducted by researchers from Mount Sinai Medical Center in New York found that Viagra could potentially slash the risk of Alzheimer’s disease by up to 60%.

The mechanism proposed by this study suggests that Viagra suppresses an enzyme called PDE5, which is found in increased levels in the brains of individuals with Alzheimer’s.

By inhibiting this enzyme, Viagra may help mitigate the pathological processes associated with Alzheimer’s disease, offering a novel avenue for potential intervention.

This latest research adds to the growing body of evidence suggesting a potential protective effect of Viagra against Alzheimer’s disease.

However, it underscores the need for further investigation to fully understand the relationship between erectile dysfunction medications and Alzheimer’s risk and to explore potential gender differences in this association.

As scientists continue to unravel the complexities of Alzheimer’s disease and search for effective treatments and preventive measures, the findings from studies like these offer hope for future interventions that could help mitigate the burden of this devastating condition.


— Share —

— About the Author —

Leave a Reply

Up Next

New Study Reveals Link Between Depression, Anorexia, and Gut Microbiota

A recent study published in BMC Psychiatry sheds light on a potential connection between major depressive disorder (MDD), anorexia, and gut microbiota. Led by researchers at the First Hospital of Shanxi Medical University, the study suggests that individuals with both depression and anorexia exhibit distinct patterns in their gut bacteria, particularly involving the presence of a specific bacterium called Blautia.

Depression, characterized by persistent sadness and a loss of interest in daily activities, affects millions worldwide and is often accompanied by a high risk of suicide. Anorexia, marked by reduced appetite and distorted body image, commonly co-occurs with depression, complicating treatment efforts.

Gut Bacteria’s Role in Depression and Anorexia

Up Next

Beyond Chemical Imbalances: Researchers Shed Light on Social Root Causes Of Depression

In a recent letter to the editor published in Molecular Psychiatry, researchers led by Joanna Moncrieff present a compelling argument challenging the conventional understanding of depression. They assert that rather than being solely attributed to chemical imbalances in the brain, and discuss the social root causes of depression.

According to Moncrieff et al., the evidence for brain differences in depression is lacking, while there is substantial support for the influence of social and environmental factors on mental health.

They argue that the circumstances of life, such as stress and adversity, play a more significant role in shaping depressive symptoms than neuro

Up Next

Study Reveals Presence of Microplastics in Human Brain: Concerns Rise Over Health Implications

In a groundbreaking revelation, researchers from the University of New Mexico have discovered microplastics infiltrating human brain tissue, as reported in a study published in the journal Environment Health Perspectives. The study sheds light on the pervasive presence of microplastics in various organs of the body, including the kidneys, liver, and brain.

Eliseo Castillo, an associate professor leading the research, underscores the widespread distribution of microplastics in the environment, emphasizing their presence in water sources, food items, and even the air we breathe.

Previous studies have estimated that individuals ingest approximately five grams of microplastics weekly, equivalent to the weight of a credit card.

Up Next

Study Reveals Significant Genetic Link Between Treatment-Resistant Depression and Family History

In a groundbreaking study published in the journal JAMA Psychiatry, researchers have uncovered a substantial genetic link between treatment-resistant depression (TRD) and family history.

Led by Dr. Cheng-Ta Li, a professor of medicine at the National Yang-Ming Chiao Tung University in Taipei, Taiwan, the study utilized extensive national health insurance data to investigate the transmission of TRD across generations and its association with other psychiatric disorders.

The findings of the study are particularly significant, as they shed light on the hereditary nature of TRD and its implications for early intervention and treatment.

Up Next

FDA Clears Prescription Digital Therapeutic for Adults with Major Depressive Disorder

The FDA has recently cleared a groundbreaking prescription digital therapeutic, known as Rejoyn, for the treatment of major depressive disorder (MDD) symptoms in adults. This innovative therapy, developed by Otsuka Pharmaceutical Co. Ltd. in collaboration with Click Therapeutics Inc., aims to provide adjunctive care for individuals who have been prescribed antidepressants as part of clinician-managed outpatient treatment.

Rejoyn is a 6-week treatment program designed to assist individuals aged 22 years and older in regulating their emotions through a combination of clinically validated cognitive training exercises and therapeutic lessons.

The therapy utilizes digital platforms to deliver pe

Up Next

Sweet Science: How Chocolate’s Theobromine May Aid Weight Loss and Alzheimer’s Prevention

A recent study conducted by researchers at Zhengzhou University in China suggests that indulging in chocolate could offer various health benefits, including weight loss assistance and Alzheimer’s prevention.

Published in the Journal of Functional Foods, the study highlights the potential of a chemical compound found in chocolate called theobromine to positively impact both the body and the brain.

Theobromine, present in cocoa beans, boasts anti-inflammatory properties and is rich in antioxidants, making it beneficial for brain health. According to scientists, this compound can protect against Alzhei

Up Next

New Study Finds High Genetic Risk for Obesity May Require Over 14,500 Daily Steps

A recent study published in JAMA Network Open reveals a significant association between genetic risk for obesity and the amount of physical activity required to mitigate the risk.

Led by Dr. Evan Brittain, associate professor of medicine at Vanderbilt University Medical Center, the study analyzed data from 3,124 participants in the National Institutes of Health’s All of Us Research Program to explore the link between genetic predisposition to obesity and recommended step counts for reducing the genetic risk of developing the condition.

Findings from the study indicate that individuals with a higher genetic risk of obesity may need to undertake more physical activity